IL-5 Protein (AA 20-134)

N° du produit ABIN2018124

Cette protéine Recombinant IL-5 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour IL-5 Protein (AA 20-134) (ABIN2018124)

Antigène: IL-5 (IL5) (Interleukin 5 (IL5))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % by SDS-PAGE.

Détail du produit

Attributs du protein: AA 20-134

Attributs du produit: ED50 < 1.0 ng/mL, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 1.0x 10^6 units/mg.
AA 20-134, expressed with an N-terminal Met.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against 25 mM Tris, pH 8.0.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant Human Interleukin-5 (rhIL-5) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIL-5 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: IL-5 (IL5) (Interleukin 5 (IL5))

Autre désignation: Interleukin-5 (IL-5)

Sujet: Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Human Interleukin-5 (rhIL-5) produced in E. coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 116 amino acids each. A fully biologically active molecule, rhIL-5 has a molecular mass of 26.5 kDa analyzed by non-reducing SDS-PAGE.
Synonyms: EDF, BCDFII, TRF

Poids moléculaire: 26.5 kDa, observed by non-reducing SDS-PAGE.

UniProt: P05113

Pathways: Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour